Cellosaurus UAB-Pkd2 Ex15-HALO/Pkd2 delta; CAGGcre; Sstr3GFP clone 15 (CVCL_E3Y6)
| Cell line name | UAB-Pkd2 Ex15-HALO/Pkd2 delta; CAGGcre; Sstr3GFP clone 15 |
|---|---|
| Synonyms | PKD2Ex15-HALO/PKD2 delta; CAGGcre; sstr3GFP clone15 |
| Accession | CVCL_E3Y6 |
| Resource Identification Initiative | To cite this cell line use: UAB-Pkd2 Ex15-HALO/Pkd2 delta; CAGGcre; Sstr3GFP clone 15 (RRID:CVCL_E3Y6) |
| Comments | From: University of Alabama at Birmingham - Polycystic Kidney Disease center (UAB-PKD); Birmingham; USA. Characteristics: In the donor mouse an HaloTag was inserted at the C-terminus (exon 15) of one allele of Pkd2, the second allele of Pkd2 is floxed. Two transgene constructs expressing Sstr3:GFP and pCAGGCre-ER are also present (UAB-PKD). Knockout cell: Method=KO mouse; MGI; MGI:1099818; Pkd2 (Note=1 of 2 alleles; floxed). Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P0A3G2; Rhodococcus rhodochrous dhaA (Note=Mutated = HaloTag; 1 of two alleles). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. Cell type: Epithelial cell of kidney; CL=CL_0002518. |
| Species of origin | Mus musculus (Mouse) (NCBI Taxonomy: 10090) |
| Sex of cell | Male |
| Age at sampling | 1M |
| Category | Transformed cell line |
| Entry history | |
| Entry creation | 19-Dec-2024 |
| Last entry update | 10-Apr-2025 |
| Version number | 2 |