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Cellosaurus HDDF (CVCL_E3QQ)

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Cell line name HDDF
Synonyms Huntington's Disease Dermal Fibroblasts
Accession CVCL_E3QQ
Resource Identification Initiative To cite this cell line use: HDDF (RRID:CVCL_E3QQ)
Comments Doubling time: 24 hours (Note=At 7th passage), 32 hours (Note=At 20th passage), 45 hours (Note=At 30th passage), 55 hours (Note=At 40th passage) (PubMed=39218021).
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:4851; HTT; Repeat_expansion; p.Gln18[46+-1] (c.52CAG(46+-1)) (c.52CAG[(40_?)]); ClinVar=VCV000000409; Zygosity=Heterozygous (PubMed=39218021).
Disease Huntington's disease (NCIt: C82342)
Huntington disease (ORDO: Orphanet_399)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 36Y
Category Finite cell line
Publications

PubMed=39218021; DOI=10.1134/S000629792407006X
Nina A. Kraskovskaya, Anna M. Kol'tsova, Polina Parfenova, Alla N. Shatrova, Natalya M. Yartseva, Vladimir D. Nazarov, Ekaterina Devyatkina, Mikhail G. Khotin, Natalia Arkadievna Mikhailova;
Dermal fibroblast cell line from a patient with the Huntington's disease as a promising model for studying disease pathogenesis: production and characterization.
Biochemistry (Mosk.) 89:1239-1250(2024)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1