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Cellosaurus BL8 TA1 (CVCL_E3KH)

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Cell line name BL8 TA1
Synonyms TA1; A1
Accession CVCL_E3KH
Resource Identification Initiative To cite this cell line use: BL8 TA1 (RRID:CVCL_E3KH)
Comments Characteristics: Tumorigenic in mice (PubMed=2867825).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7989; NRAS (Note=With p.Gln61Lys).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Hierarchy Parent: CVCL_HA74 (BL8)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=2867825
Subrata Sinha, Christopher John Marshall, Gordon E. Neal;
Gamma-glutamyltranspeptidase and the ras-induced transformation of a rat liver cell line.
Cancer Res. 46:1440-1445(1986)

PubMed=2085791; DOI=10.1007/BF00120802
Reginald Davies, Robert F. Legg, Gordon E. Neal;
Sensitivity of the cell cycle to TGF beta 1 does not correlate with transformation of a rat liver epithelial cell line.
Cell Biol. Toxicol. 6:353-363(1990)

Entry history
Entry creation19-Dec-2024
Last entry update14-Aug-2025
Version number3