Cellosaurus cell line HyCyte SK-OV-3-Luc (CVCL

Cross-references
Cell line name	HyCyte SK-OV-3-Luc
Synonyms	Luciferase Reporter SK-OV-3 Cell Line
Accession	CVCL_E3IN
Resource Identification Initiative	To cite this cell line use: HyCyte SK-OV-3-Luc (RRID:CVCL_E3IN)
Comments	Population: Caucasian. Doubling time: 24-48 hours (Hysigen=TCH-C335L). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease	Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0532 (SK-OV-3)
Sex of cell	Female
Age at sampling	64Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; TCH-C335L
Entry history
Entry creation	19-Dec-2024
Last entry update	14-Aug-2025
Version number	2