Cellosaurus cell line HyCyte NCI-H23-Luc (CVCL

Cross-references
Cell line name	HyCyte NCI-H23-Luc
Synonyms	Luciferase Reporter NCI-H23 Cell Line
Accession	CVCL_E3I7
Resource Identification Initiative	To cite this cell line use: HyCyte NCI-H23-Luc (RRID:CVCL_E3I7)
Comments	Population: African American. Doubling time: 24-48 hours (Hysigen=TCH-C280L). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Mutation; HGNC; HGNC:795; ATM; Simple; p.Gln1919Pro (c.5756A>C); ClinVar=VCV000580726; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11389; STK11; Simple; p.Trp332Ter (c.996G>A); ClinVar=VCV000376339; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Ile (c.738G>C); ClinVar=VCV001758655; Zygosity=Homozygous (from parent cell line).
Disease	Lung adenocarcinoma (NCIt: C3512)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1547 (NCI-H23)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; TCH-C280L
Entry history
Entry creation	19-Dec-2024
Last entry update	14-Aug-2025
Version number	2