Cellosaurus cell line HyCyte K-562-Luc (CVCL

Cross-references
Cell line name	HyCyte K-562-Luc
Synonyms	Luciferase Reporter K-562 Cell Line
Accession	CVCL_E3HQ
Resource Identification Initiative	To cite this cell line use: HyCyte K-562-Luc (RRID:CVCL_E3HQ)
Comments	Population: Caucasian. Doubling time: 24-48 hours (Hysigen=TCH-C226L). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110) Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0004 (K-562)
Sex of cell	Female
Age at sampling	53Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; TCH-C226L
Entry history
Entry creation	19-Dec-2024
Last entry update	14-Aug-2025
Version number	2