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Cellosaurus SF7761-luc (CVCL_E3G3)

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Cell line name SF7761-luc
Accession CVCL_E3G3
Resource Identification Initiative To cite this cell line use: SF7761-luc (RRID:CVCL_E3G3)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Brainstem, pons; UBERON=UBERON_0000988.
Sequence variations
  • Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Lys28Met (c.83A>T) (H3.3K27M); ClinVar=VCV000376435; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Glu540Ter (c.1618G>T); Zygosity=Unspecified (from parent cell line).
Disease Diffuse intrinsic pontine glioma (NCIt: C94764)
Diffuse intrinsic pontine glioma (ORDO: Orphanet_497188)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IT45 (SF7761)
Sex of cell Female
Age at sampling 6Y
Category Telomerase immortalized cell line
Publications

PubMed=22983601; DOI=10.1007/s11060-012-0973-6
Rintaro Hashizume, Ivan Smirnov, Sharon Liu, Joanna J. Phillips, Jeanette D. Hyer, Tracy R. McKnight, Michael Wendland, Michael D. Prados, Anu Banerjee, Theodore Nicolaides, Sabine Mueller ...Show all 13 authors... , Charles David James, Nalin Gupta; Show fewer authors
Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
J. Neurooncol. 110:305-313(2012)

Entry history
Entry creation19-Dec-2024
Last entry update14-Aug-2025
Version number2