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Cellosaurus TRM-6/MSCV (CVCL_E3FB)

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Cell line name TRM-6/MSCV
Accession CVCL_E3FB
Resource Identification Initiative To cite this cell line use: TRM-6/MSCV (RRID:CVCL_E3FB)
Comments Characteristics: Control cell line for TRM-6/PDX-1 (Cellosaurus=CVCL_0562) (PubMed=10847584).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fetal pancreas; UBERON=UBERON_0003921.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_G708 (TRM-6)
Sex of cell Sex unspecified
Age at sampling 24FW
Category Transformed cell line
Publications

PubMed=10847584; DOI=10.1210/mend.14.6.0476
Pamela Itkin-Ansari, Carla Demeterco-Berggren, Stuart Bossie, Dominique Gouty, Gillian M. Beattie, Jamileh Movassat, Martin I. Mally, Alberto Hayek, Fred Levine;
PDX-1 and cell-cell contact act in synergy to promote delta-cell development in a human pancreatic endocrine precursor cell line.
Mol. Endocrinol. 14:814-822(2000)

Entry history
Entry creation19-Dec-2024
Last entry update14-Aug-2025
Version number3