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Cellosaurus Me32a-T22/2L C3-C1 WND-16 (CVCL_E3F2)

[Text version]
Cell line name Me32a-T22/2L C3-C1 WND-16
Synonyms WND-16
Accession CVCL_E3F2
Resource Identification Initiative To cite this cell line use: Me32a-T22/2L C3-C1 WND-16 (RRID:CVCL_E3F2)
Comments Genetic integration: Method=Transfection; Gene=MGI; MGI:103297; Atp7b.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=With p.His203Gln).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T22).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:869; ATP7A; Unexplicit; 4bp deletion within exon 6; Zygosity=Unspecified (PubMed=12385784).
Disease Menkes disease (NCIt: C75486)
Menkes disease (ORDO: Orphanet_565)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UT43 (Me32a-T22/2L)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=9813047; DOI=10.1074/jbc.273.47.31375
Sharon La Fontaine, Stephen D. Firth, James Camakaris, Anna Englezou, Michael B. Theophilos, Michael J. Petris, Michelle Howie, Paul J. Lockhart, Mark Greenough, Hilary Brooks, Roger Robert Reddel, Julian F.B. Mercer;
Correction of the copper transport defect of Menkes patient fibroblasts by expression of the Menkes and Wilson ATPases.
J. Biol. Chem. 273:31375-31380(1998)

Entry history
Entry creation19-Dec-2024
Last entry update14-Aug-2025
Version number2