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Cellosaurus CHO-HTPO12g (CVCL_E3EF)

[Text version]
Cell line name CHO-HTPO12g
Synonyms CHO-HTPO-12g
Accession CVCL_E3EF
Resource Identification Initiative To cite this cell line use: CHO-HTPO12g (RRID:CVCL_E3EF)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:12015; TPO.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_E3ED (CHO-HTPO12)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=2474568; DOI=10.1172/JCI114179; PMCID=PMC548896
Keith D. Kaufman, Basil Rapoport, Pui Seto, Gregorio D. Chazenbalk, Ronald P. Magnusson;
Generation of recombinant, enzymatically active human thyroid peroxidase and its recognition by antibodies in the sera of patients with Hashimoto's thyroiditis.
J. Clin. Invest. 84:394-403(1989)

PubMed=2274058; DOI=10.1210/mend-4-5-786
Daniela Patrizia Foti, Keith D. Kaufman, Gregorio D. Chazenbalk, Basil Rapoport;
Generation of a biologically active, secreted form of human thyroid peroxidase by site-directed mutagenesis.
Mol. Endocrinol. 4:786-791(1990)

Entry history
Entry creation19-Dec-2024
Last entry update14-Aug-2025
Version number2