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Cellosaurus AD293 EGFRvIII+WT (CVCL_E3DR)

[Text version]
Cell line name AD293 EGFRvIII+WT
Accession CVCL_E3DR
Resource Identification Initiative To cite this cell line use: AD293 EGFRvIII+WT (RRID:CVCL_E3DR)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Val30_Arg297del = EGFRvIII).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3236; EGFR.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9804 (AD-293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=27153109; DOI=10.1371/journal.pone.0155230; PMCID=PMC4859505
Cezary Jan Treda, Marta Popeda, Magdalena Ksiazkiewicz, Dawid Pawel Grzela, Maciej P. Walczak, Mateusz Banaszczyk, Joanna Dorota Peciak, Ewelina Anna Stoczynska-Fidelus, Piotr Rieske;
EGFR activation leads to cell death independent of PI3K/AKT/mTOR in an AD293 cell line.
PLoS ONE 11:e0155230.1-e0155230.17(2016)

Entry history
Entry creation10-Sep-2024
Last entry update14-Aug-2025
Version number4