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Cellosaurus Ker-CT-Ras-p53 (CVCL_E3DC)

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Cell line name Ker-CT-Ras-p53
Accession CVCL_E3DC
Resource Identification Initiative To cite this cell line use: Ker-CT-Ras-p53 (RRID:CVCL_E3DC)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11998; TP53 (Note=With p.Arg273His).
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4T86 (Ker-CT-Ras)
Sex of cell Male
Age at sampling <1M
Category Telomerase immortalized cell line
Publications

PubMed=19936293; DOI=10.1371/journal.pone.0007908; PMCID=PMC2774948
Melville B. Vaughan, Ruben D. Ramirez, Celine Marlin Andrews, Woodring Erik Wright, Jerry W. Shay;
H-ras expression in immortalized keratinocytes produces an invasive epithelium in cultured skin equivalents.
PLoS ONE 4:e7908.1-e7908.9(2009)

Entry history
Entry creation10-Sep-2024
Last entry update14-Aug-2025
Version number4