Cellosaurus cell line LSV5 (CVCL

Entry history
Cell line name	LSV5
Accession	CVCL_E3C4
Resource Identification Initiative	To cite this cell line use: LSV5 (RRID:CVCL_E3C4)
Comments	Doubling time: 18 hours (PubMed=8612705). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=Strain 323). Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003. Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations	Mutation; HGNC; HGNC:6493; LAMC2; Simple; p.Arg95Ter (c.283C>T); ClinVar=VCV000014555; Zygosity=Homozygous (PubMed=8612705).
Disease	Severe junctional epidermolysis bullosa 3B (NCIt: C210893) Severe generalized junctional epidermolysis bullosa (ORDO: Orphanet_79404)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=8612705; DOI=10.1006/excr.1996.0138 Corinne Miquel, Laurent Gagnoux-Palacios, Monique Durand-Clement, Matt Peter Marinkovich, Jean-Paul Ortonne, Guerrino Meneguzzi; Establishment and characterization of cell line LSV5 that retains the altered adhesive properties of human junctional epidermolysis bullosa keratinocytes. Exp. Cell Res. 224:279-290(1996)
Entry creation	10-Sep-2024
Last entry update	19-Dec-2024
Version number	2