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Cellosaurus RAW 264.7 Rb1cc1 KO (CVCL_E2WW)

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Cell line name RAW 264.7 Rb1cc1 KO
Synonyms RAW 264.7 FIP200 KO; RAW 264.7 FIP200KO
Accession CVCL_E2WW
Resource Identification Initiative To cite this cell line use: RAW 264.7 Rb1cc1 KO (RRID:CVCL_E2WW)
Comments Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1341850; Rb1cc1.
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_UL71 (RAW 264.7 LRRK2 parental)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=39812709; DOI=10.1083/jcb.202310150; PMCID=PMC11734622
Amanda Bentley-DeSousa, Agnes Roczniak-Ferguson, Shawn M. Ferguson;
A STING-CASM-GABARAP pathway activates LRRK2 at lysosomes.
J. Cell Biol. 224:e202310150.1-e202310150.25(2025)

Entry history
Entry creation10-Sep-2024
Last entry update27-Nov-2025
Version number2