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Cellosaurus RSAR001 (CVCL_E2TL)

[Text version]
Cell line name RSAR001
Synonyms RSAR1; F_PDO_000001
Accession CVCL_E2TL
Resource Identification Initiative To cite this cell line use: RSAR001 (RRID:CVCL_E2TL)
Comments Part of: Fukushima Translational Research Project Patient-Derived Organoids (F-PDO) collection.
Population: Japanese.
Doubling time: ~35 hours (PubMed=30194147).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Caution: While established by the F-PDO project, this is a cell line and not an organoid.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=30194147).
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): PubMed=36959380

Markers:
AmelogeninX,Y
CSF1PO13
D3S135815
D5S81810,12
D7S82010,12
D8S117910,15
D13S31712,13
D16S53910
D18S5115
D21S1129
FGA22
Penta D10
Penta E14
TH016,9
TPOX9
vWA17

Run an STR similarity search on this cell line
Web pages Info; FTRP; -; https://www.fmu.ac.jp/home/trc/en/contract-research-provision/f-pdo/
Publications

PubMed=30194147; DOI=10.21873/anticanres.12822
Michiyuki Hakozaki, Hirosumi Tamura, Yuu Dobashi, Aki Yoshida, Kouki Kato, Takahiro Tajino, Hitoshi Yamada, Yoichi Kaneuchi, Kiyoaki Katahira, Junji Ezaki, Satoshi Waguri ...Show all 13 authors... , Shinichi Konno, Shinya Watanabe; Show fewer authors
Establishment and characterization of a novel human clear-cell sarcoma of soft-tissue cell line, RSAR001, derived from pleural effusion of a patient with pleural dissemination.
Anticancer Res. 38:5035-5042(2018)

PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623
Samuel V. Rasmussen, Agnieszka Wozniak, Melvin Lathara, Joshua M. Goldenberg, Benjamin Michael Samudio, Lissett Ramirez Bickford, Kiyo Nagamori, Hollis Wright, Andrew D. Woods, Shefali Chauhan, Che-Jui Lee ...Show all 30 authors... , Erin R. Rudzinski, Michael K. Swift, Tadashi Kondo, David Erich Fisher, Evgeny N. Imyanitov, Isidro Machado, Antonio Llombart-Bosch, Irene L. Andrulis, Nalan Gokgoz, Jay Steven Wunder, Hiroshi Moritake, Takuro Nakamura, Ganapati Srinivasa, Khin Thway, Robin L. Jones, Paul H. Huang, Noah E. Berlow, Patrick Schoffski, Charles Keller; Show fewer authors
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma.
Br. J. Cancer 128:1941-1954(2023)

Cross-references
Cell line collections (Providers) CancerTools; 160990
Sequence databases EGA; EGAD00001008611
Entry history
Entry creation10-Sep-2024
Last entry update10-Apr-2025
Version number3