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Cellosaurus HP-15a (CVCL_E2TB)

[Text version]
Cell line name HP-15a
Accession CVCL_E2TB
Resource Identification Initiative To cite this cell line use: HP-15a (RRID:CVCL_E2TB)
Comments Population: Caucasian.
Biotechnology: Used in assay systems for the detection of HPA-15a antibodies (PubMed=20812998).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:21685; CD109 (Note=With p.Tyr703Ser = HPA-15a/Gov(b)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=20812998; DOI=10.1111/j.1365-2141.2010.08369.x
Tomoya Hayashi, Etsuko Amakishi, Nobuki Matsuyama, Kazuta Yasui, Rika Ann Furuta, Yuji Hori, Yasuo Fukumori, Shigenori Tanaka, Brian R. Curtis, Masayasu Inoue, Fumiya Hirayama;
Detection of antibodies against human platelet antigens 15a and 15b by using a cell line panel.
Br. J. Haematol. 151:402-404(2010)

Entry history
Entry creation10-Sep-2024
Last entry update14-Aug-2025
Version number4