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Cellosaurus MTC-22 (CVCL_E2T3)

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Cell line name MTC-22
Accession CVCL_E2T3
Resource Identification Initiative To cite this cell line use: MTC-22 (RRID:CVCL_E2T3)
Comments Population: Japanese.
Doubling time: 18.3 +- 3.5 hours (PubMed=38573494).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Gln1346Ter (c.4036C>T); Zygosity=Homozygous (PubMed=38573494).
  • Mutation; HGNC; HGNC:8976; PIK3CB; Simple; p.Glu1051Lys (c.3151G>A); Zygosity=Homozygous (PubMed=38573494).
Disease Ovarian clear cell adenocarcinoma (NCIt: C40078)
Clear cell adenocarcinoma of the ovary (ORDO: Orphanet_398971)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): PubMed=38573494

Markers:
AmelogeninX
CSF1PO10,11
D3S135816,17
D5S8189,12
D7S82011,12
D8S117912,13
D13S31711
D16S5399,11
D18S5117
D21S1129,33.2
FGA21,22
Penta D9,10
Penta E14,18
TH017,8
TPOX8
vWA17,18

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Publications

PubMed=38573494; DOI=10.1007/s13577-024-01058-x; PMCID=PMC11194194
Hitomi Hoshino, Daisuke Inoue, Akiko Shinagawa, Hisato Yoshida, Shohei Shigeto, Kazuyuki Matsuda, Tomoya O. Akama, Yoshio Yoshida, Motohiro Kobayashi;
Establishment of a human ovarian clear cell carcinoma cell line mutant in PIK3CB but not PIK3CA.
Hum. Cell 37:1184-1193(2024)

Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2