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Cellosaurus MCF-7GFP (CVCL_E2QM)

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Cell line name MCF-7GFP
Synonyms MCF7GFP
Accession CVCL_E2QM
Resource Identification Initiative To cite this cell line use: MCF-7GFP (RRID:CVCL_E2QM)
Comments Population: Caucasian.
Doubling time: ~20-24 hours (DSMZ=ACC-983).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-983

Markers:
AmelogeninX
CSF1PO10
D2S133821,23
D3S135816
D5S81812
D7S8208,9
D8S117910,14
D13S31711
D16S53911,12
D18S5114
D19S43313,14
D21S1130
FGA23,25
Penta D12
Penta E7,12
TH016
TPOX9,12
vWA14,15

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Publications

PubMed=29569804; DOI=10.1002/stem.2819
Catharina Melzer, Juliane von der Ohe, Ralf Hass;
In vitro fusion of normal and neoplastic breast epithelial cells with human mesenchymal stroma/stem cells partially involves tumor necrosis factor receptor signaling.
Stem Cells 36:977-989(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-983
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2