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Cellosaurus MCF-7cherry (CVCL_E2QL)

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Cell line name MCF-7cherry
Synonyms MCF7cherry
Accession CVCL_E2QL
Resource Identification Initiative To cite this cell line use: MCF-7cherry (RRID:CVCL_E2QL)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=29569804; DOI=10.1002/stem.2819
Catharina Melzer, Juliane von der Ohe, Ralf Hass;
In vitro fusion of normal and neoplastic breast epithelial cells with human mesenchymal stroma/stem cells partially involves tumor necrosis factor receptor signaling.
Stem Cells 36:977-989(2018)

Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2