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Cellosaurus NB-EbC1 (CVCL_E218)

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Cell line name NB-EbC1
Synonyms NB-EBC1; NBEbC1; NBEBC1; EbC1; EBC1
Accession CVCL_E218
Resource Identification Initiative To cite this cell line use: NB-EbC1 (RRID:CVCL_E218)
Comments Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.
Doubling time: 45 hours (PubMed=20922763).
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Misspelling: NB-EBcl; Note=Occasionally.
Misspelling: NB-Ebcl-1; Note=Occasionally.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
STR profile Source(s): COG; PubMed=20922763

Markers:
AmelogeninX,Y
CSF1PO12
D2S133819,20
D3S135817
D5S81810,12
D7S82012,14
D8S117911,13
D13S31711,12
D16S53912
D18S5115,20
D19S43314,15
D21S1127,32.2
FGA24,25
TH016,9.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Web pages Provider; CCR; -; https://www.cccells.org/PDF_Files/NB_Cell_Lines/NB-EBc1%20Cell%20Line%20Data%20Sheet.pdf
Publications

PubMed=18724359; DOI=10.1038/nature07261; PMCID=PMC2672043
Yael P. Mosse, Marci Laudenslager, Luca Longo, Kristina A. Cole, Andrew Wood, Edward Fathi Attiyeh, Michael J. Laquaglia, Rachel Sennett, Jill E. Lynch, Patrizia Perri, Genevieve Laureys ...Show all 22 authors... , Frank Speleman, Cecilia Kim, Cui-Ping Hou, Hakon Hakonarson, Ali Torkamani, Nicholas J. Schork, Garrett M. Brodeur, Gian Paolo Tonini, Eric Rappaport, Marcella Devoto, John Matthew Maris; Show fewer authors
Identification of ALK as a major familial neuroblastoma predisposition gene.
Nature 455:930-935(2008)

PubMed=20922763; DOI=10.1002/pbc.22801; PMCID=PMC3005554
Min H. Kang, Malcolm A. Smith, Christopher L. Morton, Nino Keshelava, Peter J. Houghton, Charles Patrick Reynolds;
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Pediatr. Blood Cancer 56:239-249(2011)

PubMed=28350380; DOI=10.1038/sdata.2017.33; PMCID=PMC5369315
Jo Lynne Harenza, Maura A. Diamond, Rebecca N. Adams, Michael M. Song, Heather L. Davidson, Lori S. Hart, Maiah H. Dent, Paolo Fortina, Charles Patrick Reynolds, John Matthew Maris;
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci. Data 4:170033.1-170033.8(2017)

Cross-references
Encyclopedic resources Wikidata; Q54907506
Gene expression databases GEO; GSM2371246
GEO; GSM2394378
Polymorphism and mutation databases Cosmic; 1161996
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number15