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Cellosaurus HyCyte A-549 KO-hEIF2AK2 (CVCL_E1IU)

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Cell line name HyCyte A-549 KO-hEIF2AK2
Synonyms hEIF2AK2 knockout A-549
Accession CVCL_E1IU
Resource Identification Initiative To cite this cell line use: HyCyte A-549 KO-hEIF2AK2 (RRID:CVCL_E1IU)
Comments Population: Caucasian.
Doubling time: 48-72 hours (Hysigen=CGKO-M2651).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9437; EIF2AK2.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2651
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2