| Cell line name |
SCp2 |
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| Synonyms |
scp2; SubClone petit 2 |
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| Accession |
CVCL_E1I2 |
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| Resource Identification Initiative |
To cite this cell line use: SCp2 (RRID:CVCL_E1I2) |
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| Comments |
Characteristics: When given lactogenic hormones and basement membrane ECM in serum-free medium, they arrest growth, form three-dimensional alveolar structures, and express beta-casein (CelloPub=CLPUB00773).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327. |
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| Species of origin |
Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c. |
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| Hierarchy |
Parent: CVCL_E1I1 (CID 9)
Children:
|
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| Sex of cell |
Female |
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| Age at sampling |
1Y |
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| Category |
Spontaneously immortalized cell line |
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| STR profile |
Source(s): Millipore=SCC458
Markers:| Mouse STR 1-1 | 13,14 |
| Mouse STR 1-2 | 17 |
| Mouse STR 2-1 | 16 |
| Mouse STR 3-2 | 14 |
| Mouse STR 4-2 | 21.3 |
| Mouse STR 5-5 | 14 |
| Mouse STR 6-4 | 19 |
| Mouse STR 6-7 | 12 |
| Mouse STR 7-1 | 26.2 |
| Mouse STR 8-1 | 13 |
| Mouse STR 11-2 | 18 |
| Mouse STR 12-1 | 16 |
| Mouse STR 13-1 | 16.2 |
| Mouse STR 15-3 | 22.3 |
| Mouse STR 17-2 | 16,17 |
| Mouse STR 18-3 | 17,18 |
| Mouse STR 19-2 | 13 |
| Mouse STR X-1 | 24 |
Run an STR similarity search on this cell line |
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| Publications | CLPUB00773
Pierre-Yves Desprez, Calvin D. Roskelley, Judith Campisi, Mina J. Bissell;
Isolation of functional cell lines from a mouse mammary epithelial cell strain: the importance of basement membrane and cell-cell interaction.
Mol. Cell. Differ. 1:99-110(1993) PubMed=7528920; DOI=10.1073/pnas.91.26.12378; PMCID=PMC45441
Calvin D. Roskelley, Pierre-Yves Desprez, Mina J. Bissell;
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.
Proc. Natl. Acad. Sci. U.S.A. 91:12378-12382(1994) PubMed=7760836; DOI=10.1128/MCB.15.6.3398; PMCID=PMC230574
Pierre-Yves Desprez, Eiji Hara, Mina J. Bissell, Judith Campisi;
Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1.
Mol. Cell. Biol. 15:3398-3404(1995) PubMed=9671467; DOI=10.1128/MCB.18.8.4577; PMCID=PMC109043
Pierre-Yves Desprez, Claudia Qiao Lin, Nicole Thomasset, Carolyn J. Sympson, Mina J. Bissell, Judith Campisi;
A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1.
Mol. Cell. Biol. 18:4577-4588(1998) |
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| Cross-references |
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| Cell line collections (Providers) |
Millipore; SCC458
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| Entry history |
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| Entry creation | 10-Sep-2024 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 2 |
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