Cellosaurus logo
expasy logo

Cellosaurus MDBK CD46 KO (CVCL_E1FE)

[Text][XML][JSON]
Cell line name MDBK CD46 KO
Synonyms CD46(-)MDBK
Accession CVCL_E1FE
Resource Identification Initiative To cite this cell line use: MDBK CD46 KO (RRID:CVCL_E1FE)
Comments Virology: Much less susceptible than parent cell line to infection by bovine viral diarrhea virus (BVDV) (PubMed=32781607).
Knockout cell: Method=siRNA knockdown; VGNC; VGNC:-; CD46.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Hierarchy Parent: CVCL_0421 (MDBK)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=32781607; DOI=10.3390/v12080859; PMCID=PMC7472008
Kevin P. Szillat, Susanne Koethe, Kerstin Wernike, Dirk Hoper, Martin Beer;
A CRISPR/Cas9 generated bovine CD46-knockout cell line -- a tool to elucidate the adaptability of bovine viral diarrhea viruses (BVDV).
Viruses 12:859.1-859.13(2020)

Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2