Cellosaurus cell line Ubigene T98G MCOLN1 KO (CVCL

Cross-references
Cell line name	Ubigene T98G MCOLN1 KO
Synonyms	MCOLN1 Knockout cell line (T98G)
Accession	CVCL_E1CJ
Resource Identification Initiative	To cite this cell line use: Ubigene T98G MCOLN1 KO (RRID:CVCL_E1CJ)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:13356; MCOLN1. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:16051; PARD3; Unexplicit; Ex3-20del; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu42Arg (c.125T>G); Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (from parent cell line).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0556 (T98G)
Sex of cell	Male
Age at sampling	61Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-H792
Entry history
Entry creation	10-Sep-2024
Last entry update	19-Dec-2024
Version number	2