Cellosaurus cell line Ubigene SU-DHL-4 SGK1 KO (CVCL

Cross-references
Cell line name	Ubigene SU-DHL-4 SGK1 KO
Synonyms	SGK1 Knockout cell line (SU-DHL-4)
Accession	CVCL_E1CE
Resource Identification Initiative	To cite this cell line use: Ubigene SU-DHL-4 SGK1 KO (RRID:CVCL_E1CE)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10810; SGK1. Derived from site: In situ; Peritoneal effusion; UBERON=UBERON_0001268.
Sequence variations	Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL2 (from parent cell line). Mutation; HGNC; HGNC:3527; EZH2; Simple; p.Tyr646Ser (c.1937A>C) (Y641S); ClinVar=VCV000376218; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:3527; EZH2; Simple; p.Tyr666Asn (c.1996T>A) (Y661N); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Homozygous (from parent cell line).
Disease	Diffuse large B-cell lymphoma germinal center B-cell type (NCIt: C36080) Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0539 (SU-DHL-4)
Sex of cell	Male
Age at sampling	38Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-H188
Entry history
Entry creation	10-Sep-2024
Last entry update	19-Dec-2024
Version number	2