Cellosaurus cell line Ubigene SK-OV-3 RIPK1 KO (CVCL

Cross-references
Cell line name	Ubigene SK-OV-3 RIPK1 KO
Synonyms	RIPK1 Knockout cell line (SK-OV-3)
Accession	CVCL_E1CB
Resource Identification Initiative	To cite this cell line use: Ubigene SK-OV-3 RIPK1 KO (RRID:CVCL_E1CB)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10019; RIPK1. Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease	Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0532 (SK-OV-3)
Sex of cell	Female
Age at sampling	64Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-HJ062
Entry history
Entry creation	10-Sep-2024
Last entry update	19-Dec-2024
Version number	2