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Cellosaurus PrEC LHSR (CVCL_E123)

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Cell line name PrEC LHSR
Synonyms LHSR
Accession CVCL_E123
Resource Identification Initiative To cite this cell line use: PrEC LHSR (RRID:CVCL_E123)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E3G2 (PrEC LHSR-AR)
Originate from same individual CVCL_V626 ! PrEC LH
CVCL_9U68 ! PrEC LHMK
CVCL_9U69 ! PrEC LHS
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=15604246; DOI=10.1158/0008-5472.CAN-04-2938
Raanan Berger, Phillip G. Febbo, Pradip K. Majumder, Jean J. Zhao, Shayan Mukherjee, Sabina Signoretti, K. Thirza Campbell, William Raj Sellers, Thomas McCoy Roberts, Massimo Loda, Todd Robert Golub, William Chun Hahn;
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells.
Cancer Res. 64:8867-8875(2004)

PubMed=21747944; DOI=10.1371/journal.pone.0021650; PMCID=PMC3128608
Orit Leshem, Shalom Madar, Ira Kogan-Sakin, Iris Kamer, Ido Goldstein, Ran Brosh, Yehudit Cohen, Jasmine Jacob-Hirsch, Marcelo Ehrlich, Shmuel Ben-Sasson, Naomi Goldfinger ...Show all 15 authors... , Ron Loewenthal, Ephraim Gazit, Varda Rotter, Raanan Berger; Show fewer authors
TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.
PLoS ONE 6:e21650.1-e21650.12(2011)

Cross-references
Encyclopedic resources Wikidata; Q54948346
Experimental variables resources EFO; EFO_0002797
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number12