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Cellosaurus A549 Cas9 (CVCL_DX70)

[Text version]
Cell line name A549 Cas9
Accession CVCL_DX70
Resource Identification Initiative To cite this cell line use: A549 Cas9 (RRID:CVCL_DX70)
Comments Population: Caucasian.
Characteristics: Transduced with a lentiviral vector EF1a-Bsd-T2A-Cas9-WPRE (Horizon_Discovery=HD+Cas9-001).
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Horizon_Discovery; HD+Cas9-001
Entry history
Entry creation30-Jan-2024
Last entry update30-Jan-2024
Version number1