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Cellosaurus M4T.4 (CVCL_DR62)

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Cell line name M4T.4
Synonyms M4T4
Accession CVCL_DR62
Resource Identification Initiative To cite this cell line use: M4T.4 (RRID:CVCL_DR62)
Comments Doubling time: ~24 hours (PubMed=12948546).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Microglial cell; CL=CL_0000129.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: SJL/J.
Originate from same individual CVCL_DR63 ! M4T.6
Sex of cell Male
Age at sampling 1-3D
Category Transformed cell line
Publications

PubMed=12948546; DOI=10.1016/S0165-0270(03)00145-6
Julie K. Olson, Scott S. Zamvil, Stephen D. Miller;
Efficient technique for immortalization of murine microglial cells relevant for studies in murine models of multiple sclerosis.
J. Neurosci. Methods 128:33-43(2003)

PubMed=21961028; DOI=10.2174/1877381801002010148; PMCID=PMC3180920
Jessica M. Crain, Jyoti J. Watters;
Estrogen and P2 purinergic receptor systems in microglia: therapeutic targets for neuroprotection.
Open Drug Discov. J. 2:148-167(2010)

Cross-references
Encyclopedic resources Wikidata; Q54903628
Entry history
Entry creation13-Jul-2016
Last entry update14-Aug-2025
Version number9