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Cellosaurus GENYOi001-A-2 (CVCL_DQ81)

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Cell line name GENYOi001-A-2
Synonyms PBMC1-iPS4F1 shDLL4; PBMC1-iPS4F1 DLL4
Accession CVCL_DQ81
Resource Identification Initiative To cite this cell line use: GENYOi001-A-2 (RRID:CVCL_DQ81)
Comments Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
From: Centre for Genomics and Oncological Research (GENYO); Granada; Spain.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:2910; DLL4.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9U44 (GENYOi001-A)
Sex of cell Female
Age at sampling 39Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=27346199

Markers:
AmelogeninX
CSF1PO11,12
D2S133817
D3S135816,17
D5S81811,12
D7S8209,10
D8S117913,16
D13S31711,12
D16S5399,13
D18S5110,16
D19S43312,14
D21S1130,34
FGA18,22
TH017,9
TPOX8,11
vWA15,19

Run an STR similarity search on this cell line
Web pages Provider; BNLC; -; https://www.isciii.es/documents/20119/880364/Deposito_PBMC1-iPS4F1-DLL4_v2.pdf
Provider; BNLC; -; https://www.isciii.es/documents/20119/880364/Deposito_PBMC1-iPS4F1-shDLL4.pdf
Publications

PubMed=27346199; DOI=10.1016/j.scr.2016.04.005
Federico Gonzalez-Pozas, Rosa Montes, Lourdes Lopez-Onieva, Tamara Romero, Joan Domingo-Reines, Pedro J. Real, Veronica Ramos-Mejia, Veronica Ayllon;
Generation of human pluripotent stem cell lines with suppressed expression of the Notch ligand DLL4 using short hairpin RNAs.
Stem Cell Res. 16:735-739(2016)

PubMed=29246573; DOI=10.1016/j.scr.2017.07.008
Federico Gonzalez-Pozas, Rosa Montes, Joan Domingo-Reines, Veronica Ayllon, Veronica Ramos-Mejia;
Establishment of 2 control and 2 hPSC cell lines constitutively expressing the Notch ligand DLL4.
Stem Cell Res. 25:274-277(2017)

Cross-references
Cell line databases/resources hPSCreg; GENYOi001-A-2
Encyclopedic resources Wikidata; Q54938367
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number12