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Cellosaurus SV-HCEC (CVCL_DQ72)

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Cell line name SV-HCEC
Synonyms SVHCEC; SV40-transformed Human Capillary/microvascular Endothelial Cells
Accession CVCL_DQ72
Resource Identification Initiative To cite this cell line use: SV-HCEC (RRID:CVCL_DQ72)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Brain, temporal lobe, endothelium; UBERON=UBERON_0001871+UBERON_0013694.
Cell type: Brain microvascular endothelial cell; CL=CL_2000044.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=9367354; DOI=10.1096/fasebj.11.13.9367354
Arumugam Muruganandam, Leonie Moorhouse Herx, Robert Monette, Jon P. Durkin, Danica B. Stanimirovic;
Development of immortalized human cerebromicrovascular endothelial cell line as an in vitro model of the human blood-brain barrier.
FASEB J. 11:1187-1197(1997)

PubMed=11032886; DOI=10.1046/j.1471-4159.2000.0751970.x
Sevim Duvar, Minoru Suzuki, Arumugam Muruganandam, Robert Kuan-Jen Yu;
Glycosphingolipid composition of a new immortalized human cerebromicrovascular endothelial cell line.
J. Neurochem. 75:1970-1976(2000)

Cross-references
Encyclopedic resources Wikidata; Q54970932
Entry history
Entry creation13-Jul-2016
Last entry update14-Aug-2025
Version number10