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Cellosaurus AR230-r (CVCL_DP56)

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Cell line name AR230-r
Accession CVCL_DP56
Resource Identification Initiative To cite this cell line use: AR230-r (RRID:CVCL_DP56)
Comments Population: Japanese.
Doubling time: ~30-48 hours (ATCC=CRL-3346).
Selected for resistance to: ChEBI; CHEBI_45783; Imatinib (Gleevec; STI571).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=Mu-BCR transcript (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9478 (AR230)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3346

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,13
D7S82010,11
D13S3178,10
D16S5399,13
TH016
TPOX11
vWA16,20

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Publications

PubMed=10910924; DOI=10.1182/blood.V96.3.1070
Francois-Xavier Mahon, Michael W.N. Deininger, Beate Schultheis, Jerome Chabrol, Josy Reiffers, John Michael Goldman, Junia Vaz de Melo;
Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance.
Blood 96:1070-1079(2000)

Cross-references
Cell line collections (Providers) ATCC; CRL-3346
Encyclopedic resources Wikidata; Q54750355
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number12