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Cellosaurus ST14A HTT-Q120 (CVCL_DN68)

[Text version]
Cell line name ST14A HTT-Q120
Synonyms CHDI-90000065-2; CH01137; N548 mutant cells
Accession CVCL_DN68
Resource Identification Initiative To cite this cell line use: ST14A HTT-Q120 (RRID:CVCL_DN68)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4851; HTT (Note=AA 1-548 region with 120-Q run).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic brain, forebrain, striatum; UBERON=UBERON_0006240+UBERON_0002435.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Hierarchy Parent: CVCL_M588 (ST14A)
Sex of cell Sex unspecified
Age at sampling 14FD
Category Conditionally immortalized cell line
Publications

PubMed=17195849; DOI=10.1038/nchembio852
Varma H., Voisine C., DeMarco C.T., Cattaneo E., Lo D.C., Hart A.C., Stockwell B.R.
Selective inhibitors of death in mutant huntingtin cells.
Nat. Chem. Biol. 3:99-100(2007)

Cross-references
Cell line collections (Providers) Coriell; CH01137
Encyclopedic resources Wikidata; Q54955744
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number13