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Cellosaurus CLL-1390 (CVCL_DI61)

[Text version]
Cell line name CLL-1390
Synonyms CLL1390
Accession CVCL_DI61
Resource Identification Initiative To cite this cell line use: CLL-1390 (RRID:CVCL_DI61)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 37 hours (PubMed=27257868).
Omics: Array-based CGH.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; VGNC; 39069; CDKN1B; Simple; p.Ter199fs (c.596_597insCC); Zygosity=Homozygous (PubMed=31175136).
  • Mutation; VGNC; 54168; KDM6A; Simple; p.Val1131fs (c.3390delCinsGGG); Zygosity=Homozygous (PubMed=31175136).
  • Mutation; VGNC; 47261; TET2; Simple; p.Gln965Ter (c.2893C>T); Zygosity=Homozygous (PubMed=31175136).
  • Mutation; VGNC; 47719; TP53; Simple; p.Asp60fs (c.176_177insAAGGGAGCTTGAAGGTTTCT); Zygosity=Heterozygous (PubMed=31175136).
Disease Canine leukemia (NCIt: C128120)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Markers:
Dog FHC2010235,239
Dog FHC2054151,172
Dog FHC2079275
Dog PEZ1111,119
Dog PEZ12263,271
Dog PEZ20176,180
Dog PEZ3115,131
Dog PEZ5107,115
Dog PEZ6176,179
Dog PEZ8240

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Publications

PubMed=15746063; DOI=10.1158/1078-0432.CCR-04-1944
Suter S.E., Chein M.B., von Messling V., Yip B., Cattaneo R., Vernau W., Madewell B.R., London C.A.
In vitro canine distemper virus infection of canine lymphoid cells: a prelude to oncolytic therapy for lymphoma.
Clin. Cancer Res. 11:1579-1587(2005)

PubMed=22236332; DOI=10.1111/j.1476-5829.2011.00299.x
Seiser E.L., Thomas R., Richards K.L., Kelley M.K., Moore P., Suter S.E., Breen M.
Reading between the lines: molecular characterization of five widely used canine lymphoid tumour cell lines.
Vet. Comp. Oncol. 11:30-50(2013)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Cross-references
Encyclopedic resources Wikidata; Q54813639
Gene expression databases GEO; GSM1974780
Entry history
Entry creation13-Jul-2016
Last entry update21-Mar-2023
Version number8