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Cellosaurus NCI-H3255DR (CVCL_DI56)

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Cell line name NCI-H3255DR
Synonyms H3255DR
Accession CVCL_DI56
Resource Identification Initiative To cite this cell line use: NCI-H3255DR (RRID:CVCL_DI56)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_132268; Dacomitinib (PF-00299804).
Selected for resistance to: ChEBI; CHEBI_49668; Gefitinib (ZD1839; Iressa).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DI55 (NCI-H3255GR)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=20118985; DOI=10.1038/onc.2009.526; PMCID=PMC2859699
Dalia Ercan, Kreshnik Zejnullahu, Kimio Yonesaka, Yun Xiao, Marzia Capelletti, Andrew Rogers, Eugene Lifshits, Alison Brown, Charles Lee, James Gail Christensen, David Joseph Kwiatkowski ...Show all 13 authors... , Jeffrey Adam Engelman, Pasi Antero Janne; Show fewer authors
Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor.
Oncogene 29:2346-2356(2010)

Cross-references
Encyclopedic resources Wikidata; Q54908037
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number6