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Cellosaurus LS14 (CVCL_DH87)

[Text version]
Cell line name LS14
Accession CVCL_DH87
Resource Identification Initiative To cite this cell line use: LS14 (RRID:CVCL_DH87)
Comments Characteristics: Exhibits a gene expression pattern similar to that in primary preadipocytes and are capable of terminal differentiation. Can be considered as partially-differentiated preadipocytes that can be induce to terminally differentiate and accumulate lipid droplets following incubation in serum-free medium which contains a combination of adipogenic-inducing compounds (PubMed=16195405).
Doubling time: ~96 hours (PubMed=16195405).
Cell type: Preadipocyte; CL=CL_0002334.
Disease Liposarcoma (NCIt: C3194)
Liposarcoma (ORDO: Orphanet_69078)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
Web pages Provider; UC 1819 Innovation Hub; 106025; https://web.archive.org/web/20160818055736/http://www.ipo.uc.edu/index.cfm?fuseaction=technologies.results&item_number=106025
Publications

PubMed=16195405; DOI=10.1210/en.2005-0989
Hugo E.R., Brandebourg T.D., Comstock C.E.S., Gersin K.S., Sussman J.J., Ben-Jonathan N.
LS14: a novel human adipocyte cell line that produces prolactin.
Endocrinology 147:306-313(2006)

PubMed=17426441; DOI=10.4161/cbt.6.4.3816
LaPensee E.W., Reddy S.P., Hugo E.R., Schwemberger S.J., Ben-Jonathan N.
LS14 cells: a model for chemoresistance in liposarcoma.
Cancer Biol. Ther. 6:519-524(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_DH87
Encyclopedic resources Wikidata; Q54903050
Gene expression databases GEO; GSM482561
Polymorphism and mutation databases Progenetix; CVCL_DH87
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number9