Cellosaurus cell line MGH131-1 (CVCL

Cellosaurus MGH131-1 (CVCL_DH52)

Cross-references
Cell line name	MGH131-1
Accession	CVCL_DH52
Resource Identification Initiative	To cite this cell line use: MGH131-1 (RRID:CVCL_DH52)
Comments	Omics: Transcriptomics; Microarray. Omics: Variations; Array-based CGH. Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Gene deletion; HGNC; HGNC:9884; RB1; Zygosity=Homozygous (PubMed=25758528). Mutation; HGNC; HGNC:3236; EGFR; Unexplicit; Ex19del; Zygosity=Unspecified (PubMed=25758528).
Disease	Lung small cell carcinoma (NCIt: C4917) Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_DH53 ! MGH131-2
Sex of cell	Male
Age at sampling	43Y
Category	Cancer cell line
Publications	PubMed=25758528; DOI=10.1038/ncomms7377; PMCID=PMC4357281 Matthew J. Niederst, Lecia VanDam Sequist, John T. Poirier, Craig H. Mermel, Elizabeth L. Lockerman, Angel R. Garcia, Ryohei Katayama, Carlotta Costa, Kenneth N. Ross, Teresa Moran, Emily Howe ...Show all 27 authors... , Linnea E. Fulton, Hillary E. Mulvey, Lindsay A. Bernardo, Farhiya Mohamoud, Norikatsu Miyoshi, Paul A. VanderLaan, Daniel Botelho Costa, Pasi Antero Janne, Darrell R. Borger, Sridhar Ramaswamy, Toshi Shioda, Anthony John Iafrate, Gad Getz, Charles M. Rudin, Mari Mino-Kenudson, Jeffrey Adam Engelman; Show fewer authors RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer. Nat. Commun. 6:6377.1-6377.10(2015)
Encyclopedic resources	Wikidata; Q54905476
Gene expression databases	GEO; GSM1568553 GEO; GSM1579486
Entry history
Entry creation	13-Jul-2016
Last entry update	10-Apr-2025
Version number	10