Cellosaurus cell line TY-1 (CVCL

Cellosaurus TY-1 (CVCL_DG42)

Cross-references
Cell line name	TY-1
Synonyms	TY1
Accession	CVCL_DG42
Resource Identification Initiative	To cite this cell line use: TY-1 (RRID:CVCL_DG42)
Comments	Population: Japanese. Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV). Omics: Variations; Array-based CGH. Derived from site: In situ; Pericardial effusion; UBERON=UBERON_0002409.
Disease	Primary effusion lymphoma (NCIt: C6915) Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	47Y
Category	Cancer cell line
Publications	PubMed=10421407; DOI=10.1002/(SICI)1096-9071(199908)58:4<394::AID-JMV12>3.0.CO;2-H Harutaka Katano, Yoshihiko Hoshino, Yasuyuki Morishita, Tomoko Nakamura, Hitoshi Satoh, Aikichi Iwamoto, Brian Garnet Herndier, Shigeo Mori; Establishing and characterizing a CD30-positive cell line harboring HHV-8 from a primary effusion lymphoma. J. Med. Virol. 58:394-401(1999) DOI=10.1016/B978-0-12-221970-2.50457-5 Hans Gunther Drexler; The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001) PubMed=19521981; DOI=10.1002/ijc.24521 Naoko Takahashi-Makise, Shinya Suzu, Masateru Hiyoshi, Takeo Ohsugi, Harutaka Katano, Kazuo Umezawa, Seiji Okada; Biscoclaurine alkaloid cepharanthine inhibits the growth of primary effusion lymphoma in vitro and in vivo and induces apoptosis via suppression of the NF-kappaB pathway. Int. J. Cancer 125:1464-1472(2009) PubMed=21685375; DOI=10.1182/blood-2010-12-323659; PMCID=PMC3158728 Debasmita Roy, Sang-Hoon Sin, Blossom Damania, Dirk P. Dittmer; Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines. Blood 118:e32-e39(2011)
Cell line databases/resources	cancercelllines; CVCL_DG42
Encyclopedic resources	Wikidata; Q54973445
Gene expression databases	GEO; GSM634740 GEO; GSM710425 GEO; GSM710441
Polymorphism and mutation databases	Cosmic; 1588565 Progenetix; CVCL_DG42
Entry history
Entry creation	13-Jul-2016
Last entry update	10-Apr-2025
Version number	12