Cellosaurus cell line TY-1 (CVCL

Cellosaurus TY-1 (CVCL_DG42)

Cross-references
Cell line name	TY-1
Synonyms	TY1
Accession	CVCL_DG42
Resource Identification Initiative	To cite this cell line use: TY-1 (RRID:CVCL_DG42)
Comments	Population: Japanese. Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV). Omics: Variations; Array-based CGH. Derived from site: In situ; Pericardial effusion; UBERON=UBERON_0002409.
Disease	Primary effusion lymphoma (NCIt: C6915) Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	47Y
Category	Cancer cell line
Publications	PubMed=10421407; DOI=10.1002/(SICI)1096-9071(199908)58:4<394::AID-JMV12>3.0.CO;2-H Katano H., Hoshino Y., Morishita Y., Nakamura T., Satoh H., Iwamoto A., Herndier B.G., Mori S. Establishing and characterizing a CD30-positive cell line harboring HHV-8 from a primary effusion lymphoma. J. Med. Virol. 58:394-401(1999) DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001) PubMed=19521981; DOI=10.1002/ijc.24521 Takahashi-Makise N., Suzu S., Hiyoshi M., Ohsugi T., Katano H., Umezawa K., Okada S. Biscoclaurine alkaloid cepharanthine inhibits the growth of primary effusion lymphoma in vitro and in vivo and induces apoptosis via suppression of the NF-kappaB pathway. Int. J. Cancer 125:1464-1472(2009) PubMed=21685375; DOI=10.1182/blood-2010-12-323659; PMCID=PMC3158728 Roy D., Sin S.-H., Damania B., Dittmer D.P. Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines. Blood 118:e32-e39(2011)
Cell line databases/resources	cancercelllines; CVCL_DG42
Encyclopedic resources	Wikidata; Q54973445
Gene expression databases	GEO; GSM634740 GEO; GSM710425 GEO; GSM710441
Polymorphism and mutation databases	Cosmic; 1588565 Progenetix; CVCL_DG42
Entry history
Entry creation	13-Jul-2016
Last entry update	10-Apr-2025
Version number	12