Cellosaurus cell line HH-B2 (CVCL

Cross-references
Cell line name	HH-B2
Synonyms	HHB2
Accession	CVCL_DF85
Resource Identification Initiative	To cite this cell line use: HH-B2 (RRID:CVCL_DF85)
Comments	Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV). Omics: Variations; Array-based CGH. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease	Primary effusion lymphoma (NCIt: C6915) Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=10846108; DOI=10.1128/JVI.74.13.6207-6212.2000; PMCID=PMC112123 Lyndle Gradoville, Jennifer Gerlach, Elizabeth Grogan, Duane Shedd, Sarah Nikiforow, Craig Metroka, I. George Miller Jr.; Kaposi's sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire viral lytic cycle in the HH-B2 primary effusion lymphoma cell line. J. Virol. 74:6207-6212(2000) PubMed=21685375; DOI=10.1182/blood-2010-12-323659; PMCID=PMC3158728 Debasmita Roy, Sang-Hoon Sin, Blossom Andrea Damania, Dirk P. Dittmer; Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines. Blood 118:e32-e39(2011)
Cell line databases/resources	cancercelllines; CVCL_DF85
Encyclopedic resources	Wikidata; Q54887342
Gene expression databases	GEO; GSM634738
Polymorphism and mutation databases	Progenetix; CVCL_DF85
Entry history
Entry creation	13-Jul-2016
Last entry update	10-Apr-2025
Version number	11