Cellosaurus cell line MCF7 NucLight Red (CVCL

Cross-references
Cell line name	MCF7 NucLight Red
Accession	CVCL_DF46
Resource Identification Initiative	To cite this cell line use: MCF7 NucLight Red (RRID:CVCL_DF46)
Comments	Population: Caucasian. Characteristics: Stably expresses a non-perturbing nuclear restricted red fluorescent label. Genetic integration: Method=Transduction; Gene=FPbase; DBBO8; mKate2 (Note=Bright red fluorescent protein derived from eqFP578). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Discontinued: Sartorius/Essen Biosciences; Catalog number 4524. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0031 (MCF-7)
Sex of cell	Female
Age at sampling	69Y
Category	Cancer cell line
Cell line databases/resources	cancercelllines; CVCL_DF46
Encyclopedic resources	Wikidata; Q54904450
Entry history
Entry creation	13-Jul-2016
Last entry update	14-Aug-2025
Version number	20