Cellosaurus cell line K25-iPSC (CVCL

Cellosaurus K25-iPSC (CVCL_DD63)

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Cell line name

K25-iPSC

Accession

CVCL_DD63

Resource Identification Initiative

To cite this cell line use: K25-iPSC (RRID:CVCL_DD63)

Comments

Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Unspecified (PubMed=27191603).

Disease

Parkinson disease 8, autosomal dominant (NCIt: C198605)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_DD50 (ND29802)

Sex of cell

Male

Age at sampling

52Y

Category

Induced pluripotent stem cell

STR profile

Source(s): PubMed=27191603

Markers:

Amelogenin	X,Y
CSF1PO	10,12
D5S818	11,12
D7S820	10,11
D13S317	9,12
D16S539	8,13
D21S11	29,30
TH01	7,9
TPOX	8,9
vWA	17,18

Publications

PubMed=27191603; DOI=10.1371/journal.pone.0154890; PMCID=PMC4871453
Olga Momcilovic, Renuka Sivapatham, Tal Ronnen Oron, Morten Meyer, Sean Mooney, Mahendra Surendra Rao, Xian-Min Zeng;
Derivation, characterization, and neural differentiation of integration-free induced pluripotent stem cell lines from Parkinson's disease patients carrying SNCA, LRRK2, PARK2, and GBA mutations.
PLoS ONE 11:e0154890.1-e0154890.26(2016)

Cross-references

Encyclopedic resources

Wikidata; Q54899276

Entry history

Entry creation

13-Jul-2016

Last entry update

19-Dec-2024

Version number