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Cellosaurus M2B (CVCL_DD25)

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Cell line name M2B
Accession CVCL_DD25
Resource Identification Initiative To cite this cell line use: M2B (RRID:CVCL_DD25)
Comments Characteristics: Persistently infected with proteinase K resistant BSE (PrP(BSE)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Genetic integration: Method=Transduction; Gene=VGNC; VGNC:33356; Bovine PRNP.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Hierarchy Parent: CVCL_0421 (MDBK)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=25647616; DOI=10.1371/journal.pone.0115939; PMCID=PMC4315440
Dong-Seob Tark, Hyo-Jin Kim, Michael H. Neale, Min-Jeong Kim, Hyun-Joo Sohn, Yin-Lau Lee, In-Soo Cho, Yiseok Joo, Otto Windl;
Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE).
PLoS ONE 10:e0115939.1-e0115939.11(2015)

Cross-references
Encyclopedic resources Wikidata; Q54903584
Entry history
Entry creation13-Jul-2016
Last entry update14-Aug-2025
Version number14