Cellosaurus cell line Ubigene HSC-3 IGF2BP2 KO (CVCL

Cross-references
Cell line name	Ubigene HSC-3 IGF2BP2 KO
Synonyms	IGF2BP2 Knockout cell line (HSC3)
Accession	CVCL_D9WC
Resource Identification Initiative	To cite this cell line use: Ubigene HSC-3 IGF2BP2 KO (RRID:CVCL_D9WC)
Comments	Population: Japanese. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28867; IGF2BP2. Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations	Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu120Ter (c.358G>T); Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys305fs (c.912_913insTAAG); Zygosity=Unspecified (from parent cell line).
Disease	Tongue squamous cell carcinoma (NCIt: C4648) Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1288 (HSC-3)
Sex of cell	Male
Age at sampling	64Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-H100
Entry history
Entry creation	10-Sep-2024
Last entry update	19-Dec-2024
Version number	2