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Cellosaurus KE-4 (CVCL_D884)

[Text version]
Cell line name KE-4
Synonyms KE4
Accession CVCL_D884
Resource Identification Initiative To cite this cell line use: KE-4 (RRID:CVCL_D884)
Comments Population: Japanese.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
HLA typing Source: PubMed=7671230
Class I
HLA-AA*24:02,26:01
HLA-BB*54,60
HLA-CC*01,03

Source: PubMed=9023415
Class I
HLA-AA*24:02,26:01
HLA-CC*01:01,03:02

Source: PubMed=9178645
Class I
HLA-AA*24:02,26:01
HLA-BB*54,60
HLA-CC*04:01,15:02
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1887

Markers:
AmelogeninX
CSF1PO9,11,12
D5S81811,12,14
D7S82011,12
D13S31710,11
D16S5399,10,11
TH016,7,9
TPOX9,11
vWA14,17,18

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Publications

PubMed=7671230
Nakao M., Yamana H., Imai Y., Toh Y., Toh U., Kimura A., Yanoma S., Kakegawa T., Itoh K.
HLA A2601-restricted CTLs recognize a peptide antigen expressed on squamous cell carcinoma.
Cancer Res. 55:4248-4252(1995)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9178645; DOI=10.1006/cimm.1997.1108
Nakao M., Sata M., Saitsu H., Yutani S., Kawamoto M., Kojiro M., Itoh K.
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Cell. Immunol. 177:176-181(1997)

PubMed=11115554; DOI=10.3892/ijo.18.1.157
Fujii T., Kato S., Yamana H., Tanaka Y., Fujita H., Shirouzu K., Morimatsu M.
Expression of G1 cell cycle markers and the effect of adenovirus-mediated overexpression of p21Waf-1 in squamous cell carcinoma of the esophagus.
Int. J. Oncol. 18:157-163(2001)

PubMed=14532970; DOI=10.3892/ijo.23.5.1309
Matono S., Tanaka T., Sueyoshi S., Yamana H., Fujita H., Shirouzu K.
Bystander effect in suicide gene therapy is directly proportional to the degree of gap junctional intercellular communication in esophageal cancer.
Int. J. Oncol. 23:1309-1315(2003)

PubMed=20515944; DOI=10.1158/1535-7163.MCT-09-0918; PMCID=PMC2884061
Seki N., Toh U., Sayers T.J., Fujii T., Miyagi M., Akagi Y., Kusukawa J., Kage M., Shirouzu K., Yamana H.
Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways.
Mol. Cancer Ther. 9:1842-1851(2010)

PubMed=26512696; DOI=10.3390/cancers7040881; PMCID=PMC4695881
O'Callaghan C., Fanning L.J., Barry O.P.
Hypermethylation of MAPK13 promoter in oesophageal squamous cell carcinoma is associated with loss of p38delta MAPK expression.
Cancers (Basel) 7:2124-2133(2015)

Cross-references
Cell line collections (Providers) JCRB; JCRB1887
Encyclopedic resources Wikidata; Q54899717
Entry history
Entry creation22-Oct-2012
Last entry update02-May-2024
Version number10