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Cellosaurus KE-4 (CVCL_D884)

[Text version]
Cell line name KE-4
Synonyms KE4
Accession CVCL_D884
Resource Identification Initiative To cite this cell line use: KE-4 (RRID:CVCL_D884)
Comments Population: Japanese.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
HLA typing Source: PubMed=7671230
Class I
HLA-AA*24:02,26:01
HLA-BB*54,60
HLA-CC*01,03

Source: PubMed=9023415
Class I
HLA-AA*24:02,26:01
HLA-CC*01:01,03:02

Source: PubMed=9178645
Class I
HLA-AA*24:02,26:01
HLA-BB*54,60
HLA-CC*04:01,15:02
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1887

Markers:
AmelogeninX
CSF1PO9,11,12
D5S81811,12,14
D7S82011,12
D13S31710,11
D16S5399,10,11
TH016,7,9
TPOX9,11
vWA14,17,18

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Publications

PubMed=7671230
Masanobu Nakao, Hideaki Yamana, Yasuhisa Imai, Yuji Toh, Uhi Toh, Akinori Kimura, Shunsuke Yanoma, Teruo Kakegawa, Kyogo Itoh;
HLA A2601-restricted CTLs recognize a peptide antigen expressed on squamous cell carcinoma.
Cancer Res. 55:4248-4252(1995)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Naoko Seki, Tomoaki Hoshino, Megumi Kikuchi, Akihiro Hayashi, Kyogo Itoh;
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9178645; DOI=10.1006/cimm.1997.1108
Masanobu Nakao, Michio Sata, Hideki Saitsu, Shigeru Yutani, Mayumi Kawamoto, Masamichi Kojiro, Kyogo Itoh;
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Cell. Immunol. 177:176-181(1997)

PubMed=11115554; DOI=10.3892/ijo.18.1.157
Teruhiko Fujii, Seiya Kato, Hideaki Yamana, Yuichi Tanaka, Hiromasa Fujita, Kazuo Shirouzu, Minoru Morimatsu;
Expression of G1 cell cycle markers and the effect of adenovirus-mediated overexpression of p21Waf-1 in squamous cell carcinoma of the esophagus.
Int. J. Oncol. 18:157-163(2001)

PubMed=14532970; DOI=10.3892/ijo.23.5.1309
Satoru Matono, Toshiaki Tanaka, Susumu Sueyoshi, Hideaki Yamana, Hiromasa Fujita, Kazuo Shirouzu;
Bystander effect in suicide gene therapy is directly proportional to the degree of gap junctional intercellular communication in esophageal cancer.
Int. J. Oncol. 23:1309-1315(2003)

PubMed=20515944; DOI=10.1158/1535-7163.MCT-09-0918; PMCID=PMC2884061
Naoko Seki, Uhi Toh, Thomas J. Sayers, Teruhiko Fujii, Motoshi Miyagi, Yoshito Akagi, Jingo Kusukawa, Masayoshi Kage, Kazuo Shirouzu, Hideaki Yamana;
Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways.
Mol. Cancer Ther. 9:1842-1851(2010)

PubMed=26512696; DOI=10.3390/cancers7040881; PMCID=PMC4695881
Carol O'Callaghan, Liam J. Fanning, Orla P. Barry;
Hypermethylation of MAPK13 promoter in oesophageal squamous cell carcinoma is associated with loss of p38delta MAPK expression.
Cancers (Basel) 7:2124-2133(2015)

Cross-references
Cell line collections (Providers) JCRB; JCRB1887
Encyclopedic resources Wikidata; Q54899717
Entry history
Entry creation22-Oct-2012
Last entry update02-May-2024
Version number10