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Cellosaurus NZM052 (CVCL_D838)

[Text version]
Cell line name NZM052
Synonyms NZM52
Accession CVCL_D838
Resource Identification Initiative To cite this cell line use: NZM052 (RRID:CVCL_D838)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
HLA typing Source: PubMed=32567790
Class I
HLA-AA*01:01,32:01
HLA-BB*07:02,35:01
HLA-CC*04:01,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX
CSF1PO9,11
D2S133817,25
D3S135815
D5S81812
D7S8208,12
D8S117910,14
D13S3178,11
D16S53912
D18S5112,14
D19S43314
D21S1128,31.2
FGA20,26
TH016
TPOX8
vWA15,17

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Publications

PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539
Aaron R. Jeffs, Amy C. Glover, Lynn J. Slobbe, Li Wang, Shu-Jie He, Jody A. Hazlett, Anshul Awasthi, Adele G. Woolley, Elaine S. Marshall, Wayne R. Joseph, Cristin Gregor Print ...Show all 13 authors... , Bruce Charles Baguley, Michael R. Eccles; Show fewer authors
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:e8461.1-e8461.11(2009)

PubMed=22475322; DOI=10.1186/1471-2407-12-141; PMCID=PMC3352269
Ji Eun Kim, Clare J. Stones, Wayne R. Joseph, Euphemia Yee Leung, Graeme John Finlay, Andrew N. Shelling, Wayne A. Phillips, Peter R. Shepherd, Bruce Charles Baguley;
Comparison of growth factor signalling pathway utilisation in cultured normal melanocytes and melanoma cell lines.
BMC Cancer 12:141.1-141.10(2012)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Khanh B. Tran, Gregory Gimenez, Peter Tsai, Sharada Kolekar, Euan J. Rodger, Aniruddha Chatterjee, Anower Jabed, Jen-Hsing Shih, Wayne R. Joseph, Elaine S. Marshall, Qian Wang ...Show all 15 authors... , Cristin Gregor Print, Michael R. Eccles, Bruce Charles Baguley, Peter R. Shepherd; Show fewer authors
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D838
Biological sample resources BioSample; SAMN14558344
Encyclopedic resources Wikidata; Q54931587
Polymorphism and mutation databases Cosmic; 1660295
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number15