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Cellosaurus NZM004 (CVCL_D831)

[Text version]
Cell line name NZM004
Synonyms NZM04; NZM4
Accession CVCL_D831
Resource Identification Initiative To cite this cell line use: NZM004 (RRID:CVCL_D831)
Comments Doubling time: 29.8 hours (CelloPub=CLPUB00227); 48 hours (CBA=CBA-1390).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): CBA=CBA-1390; PubMed=32567790

Markers:
AmelogeninX
CSF1PO10
D2S133817,19
D3S135815,18
D5S8189
D7S8208,9
D8S117910,13
D13S31711,13
D16S53911,12
D18S5115 (CBA=CBA-1390)
15,20 (PubMed=32567790)
D19S43312,15
D21S1129,30
FGA23,24
TH018,9.3
TPOX8,11
vWA15

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Publications

PubMed=7999427; DOI=10.1016/0959-8049(94)90188-0
Elaine S. Marshall, John H.L. Matthews, James H.F. Shaw, Johanna Nixon, Paul Tumewu, Graeme John Finlay, Karen M. Holdaway, Bruce Charles Baguley;
Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays.
Eur. J. Cancer 30A:1370-1376(1994)

PubMed=11216673; DOI=10.3727/096504001108747620
Jayamala Parmar, Elaine S. Marshall, Geoffrey A. Charters, Karen M. Holdaway, Andrew N. Shelling, Bruce Charles Baguley;
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines.
Oncol. Res. 12:149-155(2000)

PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539
Aaron R. Jeffs, Amy C. Glover, Lynn J. Slobbe, Li Wang, Shu-Jie He, Jody A. Hazlett, Anshul Awasthi, Adele G. Woolley, Elaine S. Marshall, Wayne R. Joseph, Cristin Gregor Print ...Show all 13 authors... , Bruce Charles Baguley, Michael R. Eccles; Show fewer authors
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:e8461.1-e8461.11(2009)

CLPUB00227
Liene Daukste;
Mathematical modelling of cancer cell population dynamics.
Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand

PubMed=21912889; DOI=10.1007/s10637-011-9744-z
Hamish S. Sutherland, In Young Hwang, Elaine S. Marshall, Brent S. Lindsay, William Alexander Denny, Catherine Gilchrist, Wayne R. Joseph, Debra Greenhalgh, Emma Richardson, Philip Kestell, Angela Ding, Bruce Charles Baguley;
Therapeutic reactivation of mutant p53 protein by quinazoline derivatives.
Invest. New Drugs 30:2035-2045(2012)

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Clare J. Stones, Ji Eun Kim, Wayne R. Joseph, Euphemia Yee Leung, Elaine S. Marshall, Graeme John Finlay, Andrew N. Shelling, Bruce Charles Baguley;
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=23755070; DOI=10.3389/fgene.2013.00097; PMCID=PMC3668138
Ji Eun Kim, Euphemia Yee Leung, Bruce Charles Baguley, Graeme John Finlay;
Heterogeneity of expression of epithelial-mesenchymal transition markers in melanocytes and melanoma cell lines.
Front. Genet. 4:97.1-97.8(2013)

PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952
Stacey Ann N. D'mello, Jack U. Flanagan, Taryn N. Green, Euphemia Yee Leung, Marjan E. Askarian-Amiri, Wayne R. Joseph, Michael R. McCrystal, Richard J. Isaacs, James H.F. Shaw, Christopher E. Furneaux, Matthew John During ...Show all 14 authors... , Graeme John Finlay, Bruce Charles Baguley, Maggie Lucy Kalev-Zylinska; Show fewer authors
Evidence that GRIN2A mutations in melanoma correlate with decreased survival.
Front. Oncol. 3:333.1-333.9(2014)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Khanh B. Tran, Gregory Gimenez, Peter Tsai, Sharada Kolekar, Euan J. Rodger, Aniruddha Chatterjee, Anower Jabed, Jen-Hsing Shih, Wayne R. Joseph, Elaine S. Marshall, Qian Wang ...Show all 15 authors... , Cristin Gregor Print, Michael R. Eccles, Bruce Charles Baguley, Peter R. Shepherd; Show fewer authors
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line collections (Providers) CBA; CBA-1390
Cell line databases/resources cancercelllines; CVCL_D831
Biological sample resources BioSample; SAMN07624445
BioSample; SAMN14558315
Encyclopedic resources Wikidata; Q54931572
Polymorphism and mutation databases Cosmic; 2007645
Cosmic; 2141925
IARC_TP53; 14964
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number22