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Cellosaurus NZM020 (CVCL_D824)

[Text version]
Cell line name NZM020
Synonyms NZM20
Accession CVCL_D824
Resource Identification Initiative To cite this cell line use: NZM020 (RRID:CVCL_D824)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133816,19
D3S135814
D5S81812
D7S8208
D8S117912
D13S31710,12
D16S53911
D18S5116
D19S43312,15
D21S1131,32
FGA25
TH016
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539
Aaron R. Jeffs, Amy C. Glover, Lynn J. Slobbe, Li Wang, Shu-Jie He, Jody A. Hazlett, Anshul Awasthi, Adele G. Woolley, Elaine S. Marshall, Wayne R. Joseph, Cristin Gregor Print ...Show all 13 authors... , Bruce Charles Baguley, Michael R. Eccles; Show fewer authors
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:e8461.1-e8461.11(2009)

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Clare J. Stones, Ji Eun Kim, Wayne R. Joseph, Euphemia Yee Leung, Elaine S. Marshall, Graeme John Finlay, Andrew N. Shelling, Bruce Charles Baguley;
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=23755070; DOI=10.3389/fgene.2013.00097; PMCID=PMC3668138
Ji Eun Kim, Euphemia Yee Leung, Bruce Charles Baguley, Graeme John Finlay;
Heterogeneity of expression of epithelial-mesenchymal transition markers in melanocytes and melanoma cell lines.
Front. Genet. 4:97.1-97.8(2013)

PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952
Stacey Ann N. D'mello, Jack U. Flanagan, Taryn N. Green, Euphemia Yee Leung, Marjan E. Askarian-Amiri, Wayne R. Joseph, Michael R. McCrystal, Richard J. Isaacs, James H.F. Shaw, Christopher E. Furneaux, Matthew John During ...Show all 14 authors... , Graeme John Finlay, Bruce Charles Baguley, Maggie Lucy Kalev-Zylinska; Show fewer authors
Evidence that GRIN2A mutations in melanoma correlate with decreased survival.
Front. Oncol. 3:333.1-333.9(2014)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Khanh B. Tran, Gregory Gimenez, Peter Tsai, Sharada Kolekar, Euan J. Rodger, Aniruddha Chatterjee, Anower Jabed, Jen-Hsing Shih, Wayne R. Joseph, Elaine S. Marshall, Qian Wang ...Show all 15 authors... , Cristin Gregor Print, Michael R. Eccles, Bruce Charles Baguley, Peter R. Shepherd; Show fewer authors
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D824
Biological sample resources BioSample; SAMN14558325
Encyclopedic resources Wikidata; Q54931544
Polymorphism and mutation databases Cosmic; 2007657
Cosmic; 2141927
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number19