Cellosaurus logo
expasy logo

Cellosaurus NZM001 (CVCL_D815)

[Text version]
Cell line name NZM001
Synonyms NZM01; NZM1
Accession CVCL_D815
Resource Identification Initiative To cite this cell line use: NZM001 (RRID:CVCL_D815)
Comments Doubling time: 60 hours (PubMed=7718330); 70-80 hours (CBA=CBA-1389).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Obturator lymph node; UBERON=UBERON_0035171.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D823 ! NZM002
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): CBA=CBA-1389; PubMed=32567790

Markers:
AmelogeninX
CSF1PO10
D2S133817,23
D3S135817
D5S81811
D7S82011,12
D8S117913,15
D13S31710,11
D16S5399,12
D18S5119
D19S43313,15
D21S1127,32.2
FGA21,23
TH016,8
TPOX10,12
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=7999427; DOI=10.1016/0959-8049(94)90188-0
Elaine S. Marshall, John H.L. Matthews, James H.F. Shaw, Johanna Nixon, Paul Tumewu, Graeme John Finlay, Karen M. Holdaway, Bruce Charles Baguley;
Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays.
Eur. J. Cancer 30A:1370-1376(1994)

PubMed=7718330; DOI=10.1016/0959-8049(94)00472-H
Bruce Charles Baguley, Elaine S. Marshall, John Richard Whittaker, M.C. Dotchin, Johanna Nixon, Michael R. McCrystal, Graeme John Finlay, John H.L. Matthews, Karen M. Holdaway, Pierre Leonardus van Zijl;
Resistance mechanisms determining the in vitro sensitivity to paclitaxel of tumour cells cultured from patients with ovarian cancer.
Eur. J. Cancer 31A:230-237(1995)

PubMed=11216673; DOI=10.3727/096504001108747620
Jayamala Parmar, Elaine S. Marshall, Geoffrey A. Charters, Karen M. Holdaway, Andrew N. Shelling, Bruce Charles Baguley;
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines.
Oncol. Res. 12:149-155(2000)

PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539
Aaron R. Jeffs, Amy C. Glover, Lynn J. Slobbe, Li Wang, Shu-Jie He, Jody A. Hazlett, Anshul Awasthi, Adele G. Woolley, Elaine S. Marshall, Wayne R. Joseph, Cristin Gregor Print ...Show all 13 authors... , Bruce Charles Baguley, Michael R. Eccles; Show fewer authors
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:e8461.1-e8461.11(2009)

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Clare J. Stones, Ji Eun Kim, Wayne R. Joseph, Euphemia Yee Leung, Elaine S. Marshall, Graeme John Finlay, Andrew N. Shelling, Bruce Charles Baguley;
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952
Stacey Ann N. D'mello, Jack U. Flanagan, Taryn N. Green, Euphemia Yee Leung, Marjan E. Askarian-Amiri, Wayne R. Joseph, Michael R. McCrystal, Richard J. Isaacs, James H.F. Shaw, Christopher E. Furneaux, Matthew John During ...Show all 14 authors... , Graeme John Finlay, Bruce Charles Baguley, Maggie Lucy Kalev-Zylinska; Show fewer authors
Evidence that GRIN2A mutations in melanoma correlate with decreased survival.
Front. Oncol. 3:333.1-333.9(2014)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Khanh B. Tran, Gregory Gimenez, Peter Tsai, Sharada Kolekar, Euan J. Rodger, Aniruddha Chatterjee, Anower Jabed, Jen-Hsing Shih, Wayne R. Joseph, Elaine S. Marshall, Qian Wang ...Show all 15 authors... , Cristin Gregor Print, Michael R. Eccles, Bruce Charles Baguley, Peter R. Shepherd; Show fewer authors
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line collections (Providers) CBA; CBA-1389
Biological sample resources BioSample; SAMN07624439
BioSample; SAMN14558285
Encyclopedic resources Wikidata; Q54931518
Polymorphism and mutation databases Cosmic; 2007642
Cosmic; 2141929
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number19