Cellosaurus cell line NZOV11 (CVCL

Cellosaurus NZOV11 (CVCL_D810)

Cross-references
Cell line name	NZOV11
Synonyms	NZOV-11; New Zealand OVarian line 11
Accession	CVCL_D810
Resource Identification Initiative	To cite this cell line use: NZOV11 (RRID:CVCL_D810)
Comments	Miscellaneous: This cell line was originally classified as originating from an ovarian serous surface papillary adenocarcinoma and has been reclassified as a peritoneal serous papillary adenocarcinoma The reason being that serous surface papillary adenocarcinoma is no longer considered an ovarian primary tumor. The assumption is that all cases have peritoneal primaries. Derived from site: Metastatic; Ovary; UBERON=UBERON_0000992.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=21912889).
Disease	Primary peritoneal serous papillary adenocarcinoma (NCIt: C7695) Primary peritoneal carcinoma (ORDO: Orphanet_168829)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	31Y
Category	Cancer cell line
Publications	PubMed=7718330; DOI=10.1016/0959-8049(94)00472-H Bruce Charles Baguley, Elaine S. Marshall, John Richard Whittaker, M.C. Dotchin, Johanna Nixon, Michael R. McCrystal, Graeme John Finlay, John H.L. Matthews, Karen M. Holdaway, Pierre Leonardus van Zijl; Resistance mechanisms determining the in vitro sensitivity to paclitaxel of tumour cells cultured from patients with ovarian cancer. Eur. J. Cancer 31A:230-237(1995) PubMed=19493612; DOI=10.1016/j.canlet.2009.05.010 Anassuya Ramachandran, Elaine S. Marshall, Donald R. Love, Bruce Charles Baguley, Andrew N. Shelling; Activin is a potent growth suppressor of epithelial ovarian cancer cells. Cancer Lett. 285:157-165(2009) PubMed=21912889; DOI=10.1007/s10637-011-9744-z Hamish S. Sutherland, In Young Hwang, Elaine S. Marshall, Brent S. Lindsay, William Alexander Denny, Catherine Gilchrist, Wayne R. Joseph, Debra Greenhalgh, Emma Richardson, Philip Kestell, Angela Ding, Bruce Charles Baguley; Therapeutic reactivation of mutant p53 protein by quinazoline derivatives. Invest. New Drugs 30:2035-2045(2012)
Cell line databases/resources	cancercelllines; CVCL_D810
Encyclopedic resources	Wikidata; Q54931646
Entry history
Entry creation	22-Oct-2012
Last entry update	14-Aug-2025
Version number	14