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Cellosaurus SVK-1 (CVCL_D805)

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Cell line name SVK-1
Synonyms SV-k1; Stria Vascularis K-1
Accession CVCL_D805
Resource Identification Initiative To cite this cell line use: SVK-1 (RRID:CVCL_D805)
Comments Characteristics: At the permissive temperature (33 Celsius) capable of rapid proliferation in the presence of interferon gamma (IFNG). At the restrictive temperature (39 Celsius) have the potential to differentiate in the absence of IFNG.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Ear, inner ear, cochlea, stria vascularis; UBERON=UBERON_0002282.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
Sex of cell Sex unspecified
Age at sampling 2W
Category Conditionally immortalized cell line
Publications

CLPUB00246
Inna A. Belyantseva, Gilda M. Kalinec, Federico Kalinec, Bechara Kachar;
In vitro differentiation of two immortalized cell lines derived from the stria vascularis of a transgenic mouse.
(In conference) Proceedings of the Association for Research in Otolaryngology 21st midwinter meeting; pp.A620-A620; Association for Research in Otolaryngology; St. Petersburg Beach; USA (1998)

PubMed=12382283; DOI=10.1002/neu.10111
Marcelo N. Rivolta, Matthew C. Holley;
Cell lines in inner ear research.
J. Neurobiol. 53:306-318(2002)

Cross-references
Cell line collections (Providers) ABM; T0784
Encyclopedic resources Wikidata; Q54971016
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number14